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Effect of temperature and duration of storage on the stability of polyfluoroalkyl chemicals in human serum

Kato, Kayoko ; Wong, Lee-Yang ; Basden, Brian J ; Calafat, Antonia M

Chemosphere, April 2013, Vol.91(2), pp.115-117 [Peer Reviewed Journal]

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  • Title:
    Effect of temperature and duration of storage on the stability of polyfluoroalkyl chemicals in human serum
  • Author/Creator: Kato, Kayoko ; Wong, Lee-Yang ; Basden, Brian J ; Calafat, Antonia M
  • Language: English
  • Subjects: Polyfluoroalkyl Chemicals ; Stability ; Storage Temperature ; Biomonitoring ; Chemistry ; Ecology
  • Is Part Of: Chemosphere, April 2013, Vol.91(2), pp.115-117
  • Description: ► To assess the potential impact of temperature on the long-term stability of polyfluoroalkyl chemicals in serum. ► Levels of polyfluoroalkyl chemicals in human serum remained unchanged even when serum was kept at room temperature for 10 days. We assessed the potential impact of temperature on the long-term stability of several polyfluoroalkyl chemicals in serum. We evaluated the concentrations of perfluorooctane sulfonate, perfluorohexane sulfonate, perfluorooctanoate and perfluorononanoate in 16 human serum samples stored at room temperature, 5 °C, −20 °C and −70 °C at several time points during an eight month period. Concentrations of the target analytes remained unchanged under all studied conditions, even when serum was kept at room temperature for 10 days.
  • Identifier: ISSN: 0045-6535 ; E-ISSN: 1879-1298 ; DOI: 10.1016/j.chemosphere.2012.11.013