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Vitamin D status, body composition and hypertensive target organ damage in primary hypertension

Pludowski, Pawel ; Jaworski, Maciej ; Niemirska, Anna ; Litwin, Mieczyslaw ; Szalecki, Mieczyslaw ; Karczmarewicz, Elżbieta ; Michalkiewicz, Jacek

Journal of Steroid Biochemistry and Molecular Biology, October 2014, Vol.144, pp.180-184 [Peer Reviewed Journal]

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  • Title:
    Vitamin D status, body composition and hypertensive target organ damage in primary hypertension
  • Author/Creator: Pludowski, Pawel ; Jaworski, Maciej ; Niemirska, Anna ; Litwin, Mieczyslaw ; Szalecki, Mieczyslaw ; Karczmarewicz, Elżbieta ; Michalkiewicz, Jacek
  • Language: English
  • Subjects: Primary Hypertension ; Body Composition ; 25(Oh)D Level ; Vitamin D ; Left Ventricular Hypertrophy ; Carotid Intima-Media Thickness ; Chemistry
  • Is Part Of: Journal of Steroid Biochemistry and Molecular Biology, October 2014, Vol.144, pp.180-184
  • Description: Overweight/obesity and high blood pressure during growth period are important risk factors of cardiovascular disease later in life. Cardiovascular system, fat and muscles are among target tissues for vitamin D and low 25(OH)D levels are likely to attenuate potential benefits of its action. The study was aimed to evaluate vitamin D status and body composition in children and adolescents with primary hypertension (PH). The study population comprised 78 patients aged 15.4 ± 2.3 yrs (9–18 yrs; 15 girls) with diagnosed PH. Total 25(OH)D and parathyroid hormone (PTH) were assayed by Cobas e411 machine (Roche Diagnostics). DXA (Prodigy, GE Lunar) was used to assess total body bone mineral content (TBBMC; g), total body bone mineral density (TBBMD; g/cm ), lean body mass (LBM; g), % lean body mass (%LBM), fat mass (FM; g), % fat mass (% FM), Android %Fat, Gynoid %Fat and Trunk fat mass (Trunk...
  • Identifier: ISSN: 0960-0760 ; E-ISSN: 1879-1220 ; DOI: 10.1016/j.jsbmb.2013.10.026