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Vitamin D supplementation improves waist-to-hip ratio and fasting blood glucose in vitamin D deficient, overweight or obese Asians: A pilot secondary analysis of a randomised controlled trial

Scott, David ; Mousa, Aya ; Naderpoor, Negar ; de Courten, Maximilian P.J ; Scragg, Robert ; de Courten, Barbora

Journal of Steroid Biochemistry and Molecular Biology, February 2019, Vol.186, pp.136-141 [Peer Reviewed Journal]

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  • Title:
    Vitamin D supplementation improves waist-to-hip ratio and fasting blood glucose in vitamin D deficient, overweight or obese Asians: A pilot secondary analysis of a randomised controlled trial
  • Author/Creator: Scott, David ; Mousa, Aya ; Naderpoor, Negar ; de Courten, Maximilian P.J ; Scragg, Robert ; de Courten, Barbora
  • Language: English
  • Subjects: Vitamin D ; Supplementation ; Insulin ; Glucose ; Body Composition ; Asian ; Vitamin D ; Supplementation ; Insulin ; Glucose ; Body Composition ; Asian ; Chemistry
  • Is Part Of: Journal of Steroid Biochemistry and Molecular Biology, February 2019, Vol.186, pp.136-141
  • Description: •We previously reported no effects of vitamin D supplements in overweight/obesity.•In a subset of Asians, vitamin D improved waist-hip ratio and fasting glucose.•Other markers of insulin sensitivity and body composition did not improve.•Vitamin D supplementation may be more effective in specific ethnic groups. Recent trials do not support a role for vitamin D supplementation in prevention or treatment of type 2 diabetes mellitus, although effects may differ in Asian populations. In this pilot secondary analysis of a placebo-controlled randomised trial of overweight or obese individuals with low 25-hydroxyvitamin D (25(OH)D  50 nmol/L), we examined whether vitamin D supplementation improved insulin sensitivity or body composition in participants of Asian ethnicity. Amongst 65 trial participants, 33 reported being of Asian descent (mean ± SD age 30 ± 7 years; 67% male). Participants were block randomised to receive vitamin D (n = 14; initial bolus dose of...
  • Identifier: ISSN: 0960-0760 ; E-ISSN: 1879-1220 ; DOI: 10.1016/j.jsbmb.2018.10.006