skip to main content
Resource type Show Results with: Show Results with: Search type Index

The Broadening Application of Chemodenervation in X-Linked Dystonia-Parkinsonism (Part II): An Open-Label Experience With Botulinum Toxin-A (Dysport®) Injections for Oromandibular, Lingual, and Truncal-Axial Dystonias

Rosales, Raymond L ; Ng, Arlene R ; Santos, Mary Mildred Delgado-Delos ; Fernandez, Hubert H

International Journal of Neuroscience, 28 February 2011, Vol.121, pp.44-56 [Peer Reviewed Journal]

Full text available online

Citations Cited by
  • Title:
    The Broadening Application of Chemodenervation in X-Linked Dystonia-Parkinsonism (Part II): An Open-Label Experience With Botulinum Toxin-A (Dysport®) Injections for Oromandibular, Lingual, and Truncal-Axial Dystonias
  • Author/Creator: Rosales, Raymond L ; Ng, Arlene R ; Santos, Mary Mildred Delgado-Delos ; Fernandez, Hubert H
  • Language: English
  • Subjects: Botulinum Toxin ; Lingual ; Oromandibular ; Truncal Dystonia ; X-Linked Dystonia-Parkinsonism ; Chemistry ; Anatomy & Physiology
  • Is Part Of: International Journal of Neuroscience, 28 February 2011, Vol.121, pp.44-56
  • Description: While the majority of chemodenervation clinics worldwide typically use botulinum toxins for the treatment of common conditions such as blepharopsams, cervical dystonia, limb dystonia, and spasticity, the unusually high concentration of X-linked dystonia-parkinsonism (XDP) has allowed us to collect and describe our experience in the use of botulinum toxin type A (BoNT-A) on rarer dystonic patterns. BoNT-A (Dysport®) was injected in a total 109 dystonias of XDP. Our cohort included: 50 cases in the oromandibular area (jaw opening: 32 cases, jaw closing: 12 cases, and jaw deviation: 6 cases); 35 cases in the lingual area (tongue protrusion: 27 cases and tongue curling: 8 cases); and, 24 cases in the truncal-axial area (flexor: 12 cases, extensor: 7 cases, and lateral-extensor: 5 cases). Interestingly, pain, often a nonprominent symptom of dystonias, was frequently reported in 40/50 XDP cases with oromandibular dystonia and 18/24 XDP cases with truncal-axial dystonia. All BoNT-A procedures...
  • Identifier: ISSN: 0020-7454 ; E-ISSN: 1563-5279 ; DOI: 10.3109/00207454.2011.558260