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Associations of Fine Particulate Matter Species with Mortality in the United States: A Multicity Time-Series Analysis

Dai, Lingzhen ; Zanobetti, Antonella ; Koutrakis, Petros ; Schwartz, Joel

Environmental Health Perspectives (Online), Aug 2014, Vol.122(8), p.837 [Peer Reviewed Journal]

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  • Title:
    Associations of Fine Particulate Matter Species with Mortality in the United States: A Multicity Time-Series Analysis
  • Author/Creator: Dai, Lingzhen ; Zanobetti, Antonella ; Koutrakis, Petros ; Schwartz, Joel
  • Language: English
  • Subjects: United States–Us ; Studies ; Mortality ; Carbon ; Heart Attacks ; Outdoor Air Quality ; Potassium ; Bias ; Toxicity ; Sulfur ; Environmental Protection Agency–EPA
  • Is Part Of: Environmental Health Perspectives (Online), Aug 2014, Vol.122(8), p.837
  • Description: Background: Epidemiological studies have examined the association between PM2.5 and mortality, but uncertainty remains about the seasonal variations in PM2.5-related effects and the relative importance of species. Objectives: We estimated the effects of PM2.5 species on mortality and how infiltration rates may modify the association. Methods: Using city-season specific Poisson regression, we estimated PM2.5 effects on approximately 4.5 million deaths for all causes, cardiovascular disease (CVD), myocardial infarction (MI), stroke, and respiratory diseases in 75 U.S. cities for 2000-2006. We added interaction terms between PM2.5 and monthly average species-to-PM2.5 proportions of individual species to determine the relative toxicity of each species. We combined results across cities using multivariate meta-regression, and controlled for infiltration. Results: We estimated a 1.18% (95% CI: 0.93, 1.44%) increase in all-cause mortality, a 1.03% (95% CI: 0.65, 1.41%) increase in CVD, a 1.22%...
  • Identifier: E-ISSN: 15529924 ; DOI: 10.1289/ehp.1307568