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1
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials
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Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

Mega, Jessica L ; Stitziel, Nathan O ; Smith, J Gustav ; Chasman, Daniel I ; Caulfield, Mark J ; Devlin, James J ; Nordio, Francesco ; Hyde, Craig L ; Cannon, Christopher P ; Sacks, Frank M ; Poulter, Neil R ; Sever, Peter S ; Ridker, Paul M ; Braunwald, Eugene ; Melander, Olle ; Kathiresan, Sekar ; Sabatine, Marc S

The Lancet (British edition), 2015, Vol.385 (9984), p.2264-2271 [Peer Reviewed Journal]

England: Elsevier BV

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2
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
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Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

Khera, Amit V ; Emdin, Connor A ; Drake, Isabel ; Natarajan, Pradeep ; Bick, Alexander G ; Cook, Nancy R ; Chasman, Daniel I ; Baber, Usman ; Mehran, Roxana ; Rader, Daniel J ; Fuster, Valentin ; Boerwinkle, Eric ; Melander, Olle ; Orho-Melander, Marju ; Ridker, Paul M ; Kathiresan, Sekar

The New England journal of medicine, 2016, Vol.375 (24), p.2349-2358 [Peer Reviewed Journal]

United States: Massachusetts Medical Society

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3
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses
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A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

Ripatti, Samuli ; Tikkanen, Emmi ; Orho-Melander, Marju ; Havulinna, Aki S ; Silander, Kaisa ; Sharma, Amitabh ; Guiducci, Candace ; Perola, Markus ; Jula, Antti ; Sinisalo, Juha ; Lokki, Marja-Liisa ; Nieminen, Markku S ; Melander, Olle ; Salomaa, Veikko ; Peltonen, Leena ; Kathiresan, Sekar

The Lancet (British edition), 2010, Vol.376 (9750), p.1393-1400 [Peer Reviewed Journal]

England: Elsevier BV

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4
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
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Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

Jaiswal, Siddhartha ; Natarajan, Pradeep ; Silver, Alexander J ; Gibson, Christopher J ; Bick, Alexander G ; Shvartz, Eugenia ; McConkey, Marie ; Gupta, Namrata ; Gabriel, Stacey ; Ardissino, Diego ; Baber, Usman ; Mehran, Roxana ; Fuster, Valentin ; Danesh, John ; Frossard, Philippe ; Saleheen, Danish ; Melander, Olle ; Sukhova, Galina K ; Neuberg, Donna ; Libby, Peter ; Kathiresan, Sekar ; Ebert, Benjamin L

The New England journal of medicine, 2017, Vol.377 (2), p.111-121 [Peer Reviewed Journal]

United States: Massachusetts Medical Society

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5
Copeptin is an independent predictor of diabetic heart disease and death
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Copeptin is an independent predictor of diabetic heart disease and death

Enhörning, Sofia ; Hedblad, Bo ; Nilsson, Peter M ; Engström, Gunnar ; Melander, Olle

The American heart journal, 2015, Vol.169 (4), p.549-556.e1 [Peer Reviewed Journal]

United States: Elsevier BV

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6
Assessment of Conventional Cardiovascular Risk Factors and Multiple Biomarkers for the Prediction of Incident Heart Failure and Atrial Fibrillation
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Assessment of Conventional Cardiovascular Risk Factors and Multiple Biomarkers for the Prediction of Incident Heart Failure and Atrial Fibrillation

Smith, J. Gustav, MD ; Newton-Cheh, Christopher, MD, MPH ; Almgren, Peter, MSc ; Struck, Joachim, PhD ; Morgenthaler, Nils G., MD, PhD ; Bergmann, Andreas, PhD ; Platonov, Pyotr G., MD, PhD ; Hedblad, Bo, MD, PhD ; Engström, Gunnar, MD, PhD ; Wang, Thomas J., MD ; Melander, Olle, MD, PhD

JACC (Journal of the American College of Cardiology), 2010, Vol.56 (21), p.1712-1719 [Peer Reviewed Journal]

United States: Elsevier Inc

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7
Metabolite profiles and the risk of developing diabetes
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Metabolite profiles and the risk of developing diabetes

Wang, Thomas J ; Larson, Martin G ; Vasan, Ramachandran S ; Cheng, Susan ; Rhee, Eugene P ; McCabe, Elizabeth ; Lewis, Gregory D ; Fox, Caroline S ; Jacques, Paul F ; Fernandez, Céline ; O'Donnell, Christopher J ; Carr, Stephen A ; Mootha, Vamsi K ; Florez, Jose C ; Souza, Amanda ; Melander, Olle ; Clish, Clary B ; Gerszten, Robert E

Nature medicine, 2011, Vol.17 (4), p.448-453 [Peer Reviewed Journal]

United States: Springer Science and Business Media LLC

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8
Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies
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Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

Wood, Angela M ; Kaptoge, Stephen ; Butterworth, Adam S ; Willeit, Peter ; Warnakula, Samantha ; Bolton, Thomas ; Paige, Ellie ; Paul, Dirk S ; Sweeting, Michael ; Burgess, Stephen ; Bell, Steven ; Astle, William ; Stevens, David ; Koulman, Albert ; Selmer, Randi M ; Verschuren, W M Monique ; Sato, Shinichi ; Njølstad, Inger ; Woodward, Mark ; Salomaa, Veikko ; Nordestgaard, Børge G ; Yeap, Bu B ; Fletcher, Astrid ; Melander, Olle ; Kuller, Lewis H ; Balkau, Beverley ; Marmot, Michael ; Koenig, Wolfgang ; Casiglia, Edoardo ; Cooper, Cyrus ; Arndt, Volker ; Franco, Oscar H ; Wennberg, Patrik ; Gallacher, John ; de la Cámara, Agustín Gómez ; Völzke, Henry ; Dahm, Christina C ; Dale, Caroline E ; Bergmann, Manuela M ; Crespo, Carlos J ; van der Schouw, Yvonne T ; Kaaks, Rudolf ; Simons, Leon A ; Lagiou, Pagona ; Schoufour, Josje D ; Boer, Jolanda M A ; Key, Timothy J ; Rodriguez, Beatriz ; Moreno-Iribas, Conchi ; Davidson, Karina W ; Taylor, James O ; Sacerdote, Carlotta ; Wallace, Robert B ; Quiros, J Ramon ; Tumino, Rosario ; Blazer, Dan G ; Linneberg, Allan ; Daimon, Makoto ; Panico, Salvatore ; Howard, Barbara ; Skeie, Guri ; Strandberg, Timo ; Weiderpass, Elisabete ; Nietert, Paul J ; Psaty, Bruce M ; Kromhout, Daan ; Salamanca-Fernandez, Elena ; Kiechl, Stefan ; Krumholz, Harlan M ; Grioni, Sara ; Palli, Domenico ; Huerta, José M ; Price, Jackie ; Sundström, Johan ; Arriola, Larraitz ; Arima, Hisatomi ; Travis, Ruth C ; Panagiotakos, Demosthenes B ; Karakatsani, Anna ; Trichopoulou, Antonia ; Kühn, Tilman ; Grobbee, Diederick E ; Barrett-Connor, Elizabeth ; van Schoor, Natasja ; Boeing, Heiner ; Overvad, Kim ; Kauhanen, Jussi ; Wareham, Nick ; Langenberg, Claudia ; Forouhi, Nita ; Wennberg, Maria ; Després, Jean-Pierre ; Cushman, Mary ; Cooper, Jackie A ; Rodriguez, Carlos J ; Sakurai, Masaru ; Shaw, Jonathan E ; Knuiman, Matthew ; Voortman, Trudy ; Meisinger, Christa ; ...

The Lancet (British edition), 2018-04-14, Vol.391 (10129), p.1513-1523 [Peer Reviewed Journal]

England: Elsevier BV

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9
Human metabolic individuality in biomedical and pharmaceutical research
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Human metabolic individuality in biomedical and pharmaceutical research

Suhre, Karsten ; Shin, So-Youn ; Petersen, Ann-Kristin ; Mohney, Robert P ; Meredith, David ; Wägele, Brigitte ; Altmaier, Elisabeth ; Deloukas, Panos ; Erdmann, Jeanette ; Grundberg, Elin ; Hammond, Christopher J ; de Angelis, Martin Hrabé ; Kastenmüller, Gabi ; Köttgen, Anna ; Kronenberg, Florian ; Mangino, Massimo ; Meisinger, Christa ; Meitinger, Thomas ; Mewes, Hans-Werner ; Milburn, Michael V ; Prehn, Cornelia ; Raffler, Johannes ; Ried, Janina S ; Römisch-Margl, Werner ; Samani, Nilesh J ; Small, Kerrin S ; -Erich Wichmann, H ; Zhai, Guangju ; Illig, Thomas ; Spector, Tim D ; Adamski, Jerzy ; Soranzo, Nicole ; Gieger, Christian

Nature (London), 2011, Vol.477 (7362), p.54-60 [Peer Reviewed Journal]

England: Springer Science and Business Media LLC

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10
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Musunuru, Kiran ; Strong, Alanna ; Frank-Kamenetsky, Maria ; Lee, Noemi E ; Ahfeldt, Tim ; Sachs, Katherine V ; Li, Xiaoyu ; Li, Hui ; Kuperwasser, Nicolas ; Ruda, Vera M ; Pirruccello, James P ; Muchmore, Brian ; Prokunina-Olsson, Ludmila ; Hall, Jennifer L ; Schadt, Eric E ; Morales, Carlos R ; Lund-Katz, Sissel ; Phillips, Michael C ; Wong, Jamie ; Cantley, William ; Racie, Timothy ; Ejebe, Kenechi G ; Orho-Melander, Marju ; Melander, Olle ; Koteliansky, Victor ; Fitzgerald, Kevin ; Krauss, Ronald M ; Cowan, Chad A ; Kathiresan, Sekar ; Rader, Daniel J

Nature (London), 2010, Vol.466 (7307), p.714-719 [Peer Reviewed Journal]

England: Springer Science and Business Media LLC

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11
Lp-PLA2 activity and mass and CRP are associated with incident symptomatic peripheral arterial disease
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Lp-PLA2 activity and mass and CRP are associated with incident symptomatic peripheral arterial disease

Fatemi, Shahab ; Gottsäter, Anders ; Zarrouk, Moncef ; Engström, Gunnar ; Melander, Olle ; Persson, Margaretha ; Acosta, Stefan

Scientific reports, 2019, Vol.9 (1), p.1-6 [Peer Reviewed Journal]

London: Springer Science and Business Media LLC

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12
Genetic Associations with Valvular Calcification and Aortic Stenosis
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Genetic Associations with Valvular Calcification and Aortic Stenosis

Thanassoulis, George ; Campbell, Catherine Y ; Owens, David S ; Smith, J. Gustav ; Smith, Albert V ; Peloso, Gina M ; Kerr, Kathleen F ; Pechlivanis, Sonali ; Budoff, Matthew J ; Harris, Tamara B ; Malhotra, Rajeev ; O'Brien, Kevin D ; Kamstrup, Pia R ; Nordestgaard, Børge G ; Tybjaerg-Hansen, Anne ; Allison, Matthew A ; Aspelund, Thor ; Criqui, Michael H ; Heckbert, Susan R ; Hwang, Shih-Jen ; Liu, Yongmei ; Sjogren, Marketa ; van der Pals, Jesper ; Kälsch, Hagen ; Mühleisen, Thomas W ; Nöthen, Markus M ; Cupples, L. Adrienne ; Caslake, Muriel ; Di Angelantonio, Emanuele ; Danesh, John ; Rotter, Jerome I ; Sigurdsson, Sigurdur ; Wong, Quenna ; Erbel, Raimund ; Kathiresan, Sekar ; Melander, Olle ; Gudnason, Vilmundur ; O'Donnell, Christopher J ; Post, Wendy S

The New England journal of medicine, 2013, Vol.368 (6), p.503-512 [Peer Reviewed Journal]

United States: Massachusetts Medical Society

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13
Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events
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Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events

Kathiresan, Sekar ; Melander, Olle ; Anevski, Dragi ; Guiducci, Candace ; Burtt, Noël P ; Roos, Charlotta ; Hirschhorn, Joel N ; Berglund, Göran ; Hedblad, Bo ; Groop, Leif ; Altshuler, David M ; Newton-Cheh, Christopher ; Orho-Melander, Marju

The New England Journal of Medicine, 2008-03-20, Vol.358 (12), p.1240-1249 [Peer Reviewed Journal]

United States: Massachusetts Medical Society

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14
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
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Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Furberg, Helena ; Kim, Yunjung ; Dackor, Jennifer ; Boerwinkle, Eric ; Franceschini, Nora ; Ardissino, Diego ; Bernardinelli, Luisa ; Mannucci, Pier ; Mauri, Francesco ; Merlini, Piera ; Absher, Devin ; Assimes, Themistocles ; Fortmann, Stephen ; Iribarren, Carlos ; Knowles, Joshua ; Quertermous, Thomas ; Ferrucci, Luigi ; Tanaka, Toshiko ; Bis, Joshua ; Haritunians, Talin ; McKnight, Barbara ; Psaty, Bruce ; Taylor, Kent ; Thacker, Evan ; Almgren, Peter ; Groop, Leif ; Ladenvall, Claes ; Boehnke, Michael ; Jackson, Anne ; Mohlke, Karen ; Stringham, Heather ; Tuomilehto, Jaakko ; Benjamin, Emelia ; Hwang, S.J ; Levy, Daniel ; Preis, S.R ; Vasan, Ramachanan Srini ; Duan, Jubao ; Gejman, Pablo ; Levinson, Douglas ; Sanders, Alan ; Shi, Jianxin ; Lips, Esther ; McKay, James ; Agudo, Antonio ; Barzan, Luigi ; Bencko, Vladimir ; Benhamou, Simone ; Castellsagué, Xavier ; Canova, Cristina ; Conway, David ; Fabianova, Eleonora ; Foretova, Lenka ; Janout, Vladimir ; Healy, Claire ; Holcátová, Ivana ; Kjaerheim, Kristina ; Lagiou, P ; Lissowska, Jolanta ; Lowry, Ray ; MacFarlane, Tatiana ; Mates, Dana ; Richiardi, Lorenzo ; Rudnai, Peter ; Szeszenia-Dabrowska, Neonilia ; Zaridze, D ; Znaor, Ariana ; Lathrop, Mark ; Brennan, Paul ; Bandinelli, Stefania ; Frayling, Timothy ; Guralnik, Jack ; Milaneschi, Yuri ; Perry, John ; Altshuler, David ; Elosua, Roberto ; Kathiresan, Sekar ; Lucas, Gavin ; Melander, Olle ; Salomaa, Veikko ; Schwartz, Stephen ; Voight, Benjamin ; Penninx, Brenda ; Smit, Johannes ; Vogelzangs, Nicole ; Boomsma, Dorret ; Geus, Eco ; Vink, Jacqueline ; Willemsen, Gonneke ; Chanock, Stephen ; Gu, Fangyi ; Hankinson, Susan ; Hunter, David ; Hofman, Albert ; Tiemeier, Henning ; Uitterlinden, Ané ; Tikka-Kleemola, Päivi ; Walter, Stefan ; Chasman, Daniel ; Everett, Brendan ; ...

Nature genetics, 2010, Vol.42 (5), p.441-447 [Peer Reviewed Journal]

United States: Springer Science and Business Media LLC

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15
2-Aminoadipic acid is a biomarker for diabetes risk
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2-Aminoadipic acid is a biomarker for diabetes risk

Wang, Thomas J ; Ngo, Debby ; Psychogios, Nikolaos ; Dejam, Andre ; Larson, Martin G ; Vasan, Ramachandran S ; Ghorbani, Anahita ; O’Sullivan, John ; Cheng, Susan ; Rhee, Eugene P ; Sinha, Sumita ; McCabe, Elizabeth ; Fox, Caroline S ; O’Donnell, Christopher J ; Ho, Jennifer E ; Florez, Jose C ; Magnusson, Martin ; Pierce, Kerry A ; Souza, Amanda L ; Yu, Yi ; Carter, Christian ; Light, Peter E ; Melander, Olle ; Clish, Clary B ; Gerszten, Robert E

The Journal of clinical investigation, 2013, Vol.123 (10), p.4309-4317 [Peer Reviewed Journal]

United States: American Society for Clinical Investigation

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16
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
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Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

Kathiresan, Sekar ; Melander, Olle ; Guiducci, Candace ; Surti, Aarti ; Burtt, Noël P ; Rieder, Mark J ; Cooper, Gregory M ; Roos, Charlotta ; Voight, Benjamin F ; Havulinna, Aki S ; Wahlstrand, Björn ; Hedner, Thomas ; Corella, Dolores ; Tai, E Shyong ; Ordovas, Jose M ; Berglund, Göran ; Vartiainen, Erkki ; Jousilahti, Pekka ; Hedblad, Bo ; Taskinen, Marja-Riitta ; Newton-Cheh, Christopher ; Salomaa, Veikko ; Peltonen, Leena ; Groop, Leif ; Altshuler, David M ; Orho-Melander, Marju

Nature genetics, 2008, Vol.40 (2), p.189-197 [Peer Reviewed Journal]

United States: Springer Science and Business Media LLC

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17
Orthostatic Changes in Hemodynamics and Cardiovascular Biomarkers in Dysautonomic Patients
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Orthostatic Changes in Hemodynamics and Cardiovascular Biomarkers in Dysautonomic Patients

Nilsson, David ; Sutton, Richard ; Tas, Widet ; Burri, Philippe ; Melander, Olle ; Fedorowski, Artur ;Björklund, Peyman

PloS one, 2015, Vol.10 (6), p.e0128962 [Peer Reviewed Journal]

United States: Public Library of Science (PLoS)

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18
Dynamic high-sensitivity troponin elevations in atrial fibrillation patients might not be associated with significant coronary artery disease
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Dynamic high-sensitivity troponin elevations in atrial fibrillation patients might not be associated with significant coronary artery disease

Thelin, Johan ; Melander, Olle

BMC cardiovascular disorders, 2017, Vol.17 (1), p.169-9 [Peer Reviewed Journal]

England: Springer Science and Business Media LLC

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19
Atrial fibrillation in the Malmö diet and cancer study: a study of occurrence, risk factors and diagnostic validity
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Atrial fibrillation in the Malmö diet and cancer study: a study of occurrence, risk factors and diagnostic validity

Smith, J. Gustav ; Platonov, Pyotr G ; Hedblad, Bo ; Engström, Gunnar ; Melander, Olle

European journal of epidemiology, 2009, Vol.25 (2), p.95-102 [Peer Reviewed Journal]

Dordrecht: Springer Science and Business Media LLC

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20
Telomere Length Is Associated With Obesity Parameters but With a Gender Difference
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Telomere Length Is Associated With Obesity Parameters but With a Gender Difference

Nordfjäll, Katarina ; Eliasson, Mats ; Stegmayr, Birgitta ; Melander, Olle ; Nilsson, Peter ; Roos, Göran

Obesity, 2008-12, Vol.16 (12), p.2682-2689 [Peer Reviewed Journal]

Oxford, UK: Blackwell Publishing Ltd

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