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Results 1 - 20 of 12,691  for Central Connecticut State University

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1
Insulator dysfunction and oncogene activation in IDH mutant gliomas
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Insulator dysfunction and oncogene activation in IDH mutant gliomas

Flavahan, William A ; Drier, Yotam ; Liau, Brian B ; Gillespie, Shawn M ; Venteicher, Andrew S ; Stemmer-Rachamimov, Anat O ; Suvà, Mario L ; Bernstein, Bradley E

Nature (London), 2015-12-23, Vol.529 (7584), p.110-114 [Peer Reviewed Journal]

England: Springer Science and Business Media LLC

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2
Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages
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Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages

Choi, Hosoon ; Lee, Ryang Hwa ; Bazhanov, Nikolay ; Oh, Joo Youn ; Prockop, Darwin J

Blood, 2011-07-14, Vol.118 (2), p.330-338 [Peer Reviewed Journal]

United States: American Society of Hematology

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3
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody
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The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody

Benson, Don M ; Bakan, Courtney E ; Mishra, Anjali ; Hofmeister, Craig C ; Efebera, Yvonne ; Becknell, Brian ; Baiocchi, Robert A ; Zhang, Jianying ; Yu, Jianhua ; Smith, Megan K ; Greenfield, Carli N ; Porcu, Pierluigi ; Devine, Steven M ; Rotem-Yehudar, Rinat ; Lozanski, Gerard ; Byrd, John C ; Caligiuri, Michael A

Blood, 2010-09-30, Vol.116 (13), p.2286-2294 [Peer Reviewed Journal]

United States: American Society of Hematology

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4
Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation
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Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

Sigismund, Sara ; Argenzio, Elisabetta ; Tosoni, Daniela ; Cavallaro, Elena ; Polo, Simona ; Di Fiore, Pier Paolo

Developmental cell, 2008-08, Vol.15 (2), p.209-219 [Peer Reviewed Journal]

United States: Elsevier BV

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5
Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice
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Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice

Sinha, Rohit A ; Farah, Benjamin L ; Singh, Brijesh K ; Siddique, Monowarul M ; Li, Ying ; Wu, Yajun ; Ilkayeva, Olga R ; Gooding, Jessica ; Ching, Jianhong ; Zhou, Jin ; Martinez, Laura ; Xie, Sherwin ; Bay, Boon-Huat ; Summers, Scott A ; Newgard, Christopher B ; Yen, Paul M

Hepatology (Baltimore, Md.), 2014-04, Vol.59 (4), p.1366-1380 [Peer Reviewed Journal]

United States: Wiley

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6
Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein
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Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

Wong, Amy P ; Bear, Christine E ; Chin, Stephanie ; Pasceri, Peter ; Thompson, Tadeo O ; Huan, Ling-Jun ; Ratjen, Felix ; Ellis, James ; Rossant, Janet

Nature biotechnology, 2012-08-26, Vol.30 (9), p.876-882 [Peer Reviewed Journal]

United States: Springer Science and Business Media LLC

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7
The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression
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The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression

Diaz-Ruiz, Rodrigo ; Rigoulet, Michel ; Devin, Anne

Biochimica et biophysica acta. Bioenergetics, 2011-06, Vol.1807 (6), p.568-576 [Peer Reviewed Journal]

Elsevier BV

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8
Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition
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Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition

Gormally, Michael V ; Dexheimer, Thomas S ; Marsico, Giovanni ; Sanders, Deborah A ; Lowe, Christopher ; Matak-Vinković, Dijana ; Michael, Sam ; Jadhav, Ajit ; Rai, Ganesha ; Maloney, David J ; Simeonov, Anton ; Balasubramanian, Shankar

Nature communications, 2014-11-12, Vol.5 (1), p.5165-5165 [Peer Reviewed Journal]

England: Springer Science and Business Media LLC

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9
MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators
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MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

Gabriely, G ; Wurdinger, T ; Kesari, S ; Esau, C. C ; Burchard, J ; Linsley, P. S ; Krichevsky, A. M

Molecular and cellular biology, 2008-06-30, Vol.28 (17), p.5369-5380 [Peer Reviewed Journal]

United States: American Society for Microbiology

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10
Simultaneous Treatment of Human Bronchial Epithelial Cells with Serine and Cysteine Protease Inhibitors Prevents Severe Acute Respiratory Syndrome Coronavirus Entry
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Simultaneous Treatment of Human Bronchial Epithelial Cells with Serine and Cysteine Protease Inhibitors Prevents Severe Acute Respiratory Syndrome Coronavirus Entry

Kawase, M ; Shirato, K ; van der Hoek, L ; Taguchi, F ; Matsuyama, S

Journal of virology, 2012-04-11, Vol.86 (12), p.6537-6545 [Peer Reviewed Journal]

United States: American Society for Microbiology

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11
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
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Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

Pike, Lisa S ; Smift, Amy L ; Croteau, Nicole J ; Ferrick, David A ; Wu, Min

Biochimica et biophysica acta. Bioenergetics, 2011-06, Vol.1807 (6), p.726-734 [Peer Reviewed Journal]

Elsevier BV

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12
Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning
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Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning

Sheng, Rui ; Zhang, Li-Sha ; Han, Rong ; Liu, Xiao-Qian ; Gao, Bo ; Qin, Zheng-Hong

Autophagy, 2014-10-27, Vol.6 (4), p.482-494 [Peer Reviewed Journal]

United States: Informa UK Limited

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13
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

Engelman, Jeffrey A ; Chen, Liang ; Tan, Xiaohong ; Crosby, Katherine ; Guimaraes, Alexander R ; Upadhyay, Rabi ; Maira, Michel ; McNamara, Kate ; Perera, Samanthi A ; Song, Youngchul ; Chirieac, Lucian R ; Kaur, Ramneet ; Lightbown, Angela ; Simendinger, Jessica ; Li, Timothy ; Padera, Robert F ; García-Echeverría, Carlos ; Weissleder, Ralph ; Mahmood, Umar ; Cantley, Lewis C ; Wong, Kwok-Kin

Nature medicine, 2008-11-30, Vol.14 (12), p.1351-1356 [Peer Reviewed Journal]

United States: Springer Science and Business Media LLC

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14
Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl− homeostasis
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Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl− homeostasis

Ferrini, Francesco ; Trang, Tuan ; Mattioli, Theresa-Alexandra M ; Laffray, Sophie ; Del'Guidice, Thomas ; Lorenzo, Louis-Etienne ; Castonguay, Annie ; Doyon, Nicolas ; Zhang, Wenbo ; Godin, Antoine G ; Mohr, Daniela ; Beggs, Simon ; Vandal, Karen ; Beaulieu, Jean-Martin ; Cahill, Catherine M ; Salter, Michael W ; De Koninck, Yves

Nature neuroscience, 2013-01-06, Vol.16 (2), p.183-192 [Peer Reviewed Journal]

United States: Springer Science and Business Media LLC

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15
Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
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Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition

Puissant, Alexandre ; Frumm, Stacey M ; Alexe, Gabriela ; Bassil, Christopher F ; Qi, Jun ; Chanthery, Yvan H ; Nekritz, Erin A ; Zeid, Rhamy ; Gustafson, William Clay ; Greninger, Patricia ; Garnett, Matthew J ; McDermott, Ultan ; Benes, Cyril H ; Kung, Andrew L ; Weiss, William A ; Bradner, James E ; Stegmaier, Kimberly

Cancer discovery, 2013-03, Vol.3 (3), p.308-323

United States: American Association for Cancer Research (AACR)

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16
Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway
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Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway

Vucicevic, Ljubica ; Misirkic, Maja ; Kristina, Janjetovic ; Vilimanovich, Urosh ; Sudar, Emina ; Isenovic, Esma ; Prica, Marko ; Harhaji-Trajkovic, Ljubica ; Kravic-Stevovic, Tamara ; Vladimir, Bumbasirevic ; Trajkovic, Vladimir

Autophagy, 2014-10-27, Vol.7 (1), p.40-50 [Peer Reviewed Journal]

United States: Informa UK Limited

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17
The Bifunctional microRNA miR-9/miR-9 Regulates REST and CoREST and Is Downregulated in Huntington's Disease
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The Bifunctional microRNA miR-9/miR-9 Regulates REST and CoREST and Is Downregulated in Huntington's Disease

Packer, A. N ; Xing, Y ; Harper, S. Q ; Jones, L ; Davidson, B. L

The Journal of neuroscience, 2008-12-31, Vol.28 (53), p.14341-14346 [Peer Reviewed Journal]

United States: Society for Neuroscience

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18
Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo
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Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

Tan, Y ; Ichikawa, T ; Li, J ; Si, Q ; Yang, H ; Chen, X ; Goldblatt, C. S ; Meyer, C. J ; Li, X ; Cai, L ; Cui, T

Diabetes (New York, N.Y.), 2011-01-26, Vol.60 (2), p.625-633 [Peer Reviewed Journal]

United States: American Diabetes Association

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19
Mediator kinase inhibition further activates super-enhancer-associated genes in AML
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Mediator kinase inhibition further activates super-enhancer-associated genes in AML

Pelish, Henry E ; Liau, Brian B ; Nitulescu, Ioana I ; Tangpeerachaikul, Anupong ; Poss, Zachary C ; Da Silva, Diogo H ; Caruso, Brittany T ; Arefolov, Alexander ; Fadeyi, Olugbeminiyi ; Christie, Amanda L ; Du, Karrie ; Banka, Deepti ; Schneider, Elisabeth V ; Jestel, Anja ; Zou, Ge ; Si, Chong ; Ebmeier, Christopher C ; Bronson, Roderick T ; Krivtsov, Andrei V ; Myers, Andrew G ; Kohl, Nancy E ; Kung, Andrew L ; Armstrong, Scott A ; Lemieux, Madeleine E ; Taatjes, Dylan J ; Shair, Matthew D

Nature (London), 2015-09-28, Vol.526 (7572), p.273-276 [Peer Reviewed Journal]

Springer Science and Business Media LLC

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20
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

Pascual, Gabriel ; Fong, Amy L ; Ogawa, Sumito ; Gamliel, Amir ; Li, Andrew C ; Perissi, Valentina ; Rose, David W ; Willson, Timothy M ; Rosenfeld, Michael G ; Glass, Christopher K

Nature (London), 2005-08-28, Vol.437 (7059), p.759-763 [Peer Reviewed Journal]

England: Springer Science and Business Media LLC

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