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1
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Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR

Pereira Da Veiga, Sónia Rosa ; Ge, Xuemei ; Mercer, Carol A. ; Hernández Álvarez, María I. ; Elnakat Thomas, Hala ; Hernandez Losa, Javier ; Ramon Y Cajal, Santiago ; Zorzano Olarte, Antonio ; Thomas, George ; Kozma, Sara C.

https://dx.doi.org/10.1158/1078-0432.CCR-18-0177

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2
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Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis

Sia, Daniela ; Villanueva, Augusto ; Friedman, Scott L. ; Llovet I Bayer, Josep Maria

https://doi.org/10.1053/j.gastro.2016.11.048 [Peer Reviewed Journal]

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3
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Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma

Tovar, Victoria ; Cornella, Helena ; Moeini, Agrin ; Vidal, Samuel ; Hoshida, Yujin ; Sia, Daniela ; Peix, Judit ; Cabellos, Laia ; Alsinet, Clara ; Torrecilla, Sara ; Martinez Quetglas, Iris ; Lozano Salvatella, Juan José ; Desbois - Mouthon, Christele ; Sole, Manel ; Domingo - Domenech, Josep ; Villanueva, Augusto ; Llovet I Bayer, Josep Maria

https://doi.org/10.1136/gutjnl-2015-309501 [Peer Reviewed Journal]

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4
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Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma

Bollard, Julien ; Miguela, Verónica ; Ruiz De Galarreta, Marina ; Venkatesh, Anu ; Bian, C. Billie ; Roberto, Mark P. ; Tovar, Victoria ; Sia, Daniela ; Molina Sánchez, Pedro ; Nguyen, Christie B. ; Nakagawa, Shigeki ; Llovet I Bayer, Josep Maria ; Hoshida, Yujin ; Lujambio, Amaia

info:eu-repo/grantAgreement/EC/H2020/667273/EU//HEP-CAR [Peer Reviewed Journal]

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5
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Unique genomic profile of fibrolamellar hepatocellular carcinoma

Cornella, Helena ; Alsinet, Clara ; Sayols, Sergi ; Zhang, Zhongyang ; Hao, Ke ; Cabellos, Laia ; Hoshida, Yujin ; Vila Casadesús, Maria ; Villanueva, Augusto ; Thung, Swan ; Ward, Stephen C. ; Rodríguez Carunchio, Leonardo. ; Imbeaud, Sandrine ; Lachenmayer, Anja ; Quaglia, Alberto ; Nagorney David M. ; Minguez, Beatriz ; Carrilho, Flair ; Robert, Lewis R. ; Mazzaferro, Vincenzo ; Schwartz, Myron ; Esteller, Manel ; Heaton, Nigel D. ; Zucman - Rossi, Jessica ; Llovet I Bayer, Josep Maria

https://doi.org/10.1053/j.gastro.2014.12.028 [Peer Reviewed Journal]

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6
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Identification of an immune-specific class of Hepatocellular Carcinoma, based on molecular features

Sia, Daniela ; Jiao, Yang ; Martinez Quetglas, Iris ; Kuchuk, Olga ; Villacorta Martin, Carlos ; De Moura, Manuel Castro ; Putra, Juan ; Campreciós Figueras, Genís ; Bassaganyas, Laia ; Akers, Nicholas ; Losic, Bojan ; Waxman, Samuel ; Thung, Swan N. ; Mazzaferro, Vincenzo ; Esteller, Manel ; Friedman, Scott L. ; Schwartz, Myron ; Villanueva, Augusto ; Llovet I Bayer, Josep Maria

https://doi.org/10.1053/j.gastro.2017.06.007 [Peer Reviewed Journal]

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7
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BMP9 is a proliferative and survival factor for human hepatocellular carcinoma cells

Herrera, Blanca ; García Álvaro, María ; Cruz, Silvia ; Walsh, Peter ; Fernández, Margarita ; Roncero, Cesáreo ; Fabregat Romero, Isabel ; Sánchez, Aránzazu ; Inman, Gareth J.

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8
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Differential inhibition of the TGF-b signaling pathway in HCC cells using the small molecule inhibitor LY2157299 and the D10 monoclonal antibody against TGF-β receptor Type II

Dituri, Francesco ; Mazzocca, Antonio ; Peidrò, Fernando Juan ; Papappicco, Patrizia ; Fabregat Romero, Isabel ; De Santis, Flavia ; Paradiso, Angelo ; Sabbà, Carlo ; Giannelli, Gianluigi

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9
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IGF2 is up-regulated by epigenetic mechanisms in Hepatocellular Carcinoma and is an actionable oncogene product in experimental models

Martinez Quetglas, Iris ; Pinyol, Roser ; Dauch, Daniel ; Torrecilla, Sara ; Tovar, Victoria ; Moeini, Agrin ; Alsinet, Clara ; Portela, Anna ; Rodriguez Carunchio, Leonardo ; Sole, Manel ; Lujambio, Amaia ; Villanueva, Augusto ; Thung, Swan N. ; Esteller, Manel ; Zender, Lars ; Llovet I Bayer, Josep Maria

info:eu-repo/grantAgreement/EC/FP7/259744/EU//HEPTROMIC [Peer Reviewed Journal]

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10
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Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study

Fedirko, Veronika ; Tran, Hao Quang ; Gewirtz, Andrew T. ; Stepien, Magdalena ; Trichopoulou, Antonia ; Aleksandrova, Krasimira ; Olsen, Anja ; Tjønneland, Anne ; Overvad, Kim ; Carbonnel, Franck ; Boutron - Ruault, Marie - Christine ; Severi, Gianluca ; Kühn, Tilman ; Kaaks, Rudolf ; Boeing, Heiner ; Bamia, Christina ; Lagiou, Pagona ; Grioni, Sara ; Panico, Salvatore ; Palli, Domenico ; Tumino, Rosario ; Naccarati, Alessio ; Peeters, Petra H. M. ; Bueno De Mesquita, H. Bas ; Weiderpass, Elisabete ; Huerta Castaño, José María ; Barricarte, Aurelio ; Sánchez, María José ; Dorronsoro, Miren ; Quirós, J. Ramón ; Agudo, Antonio ; Sjöberg, Klas ; Ohlsson, Bodil ; Hemmingsson, Oskar ; Werner, Mårten ; Bradbury, Kathryn E. ; Khaw, Kay - Tee ; Wareham, Nicholas J. ; Tsilidis, Konstantinos K. ; Aune, Dagfinn ; Scalbert, Augustin ; Romieu, Isabelle ; Riboli, Elio ; Jenab, Mazda

https://doi.org/10.1186/s12916-017-0830-8

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11
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Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort

Fages, Anne ; Duarte Salles, Talita ; Stepien, Magdalena ; Ferrari, Pietro ; Fedirko, Veronika ; Pontoizeau, Clément ; Trichopoulou, Antonia ; Aleksandrova, Krasimira ; Tjønneland, Anne ; Olsen, Anja ; Clavel - Chapelon, Françoise ; Boutron - Ruault, Marie - Christine ; Severi, Gianluca ; Kaaks, Rudolf ; Kuhn, Tilman ; Floegel, Anna ; Boeing, Heiner ; Lagiou, Pagona ; Bamia, Christina ; Trichopoulos, Dimitrios ; Palli, Domenico ; Pala, Valeria ; Panico, Salvatore ; Tumino, Rosario ; Vineis, Paolo ; Bueno De Mesquita, H. Bas ; Peeters, Petra H. M. ; Weiderpass, Elisabete ; Agudo, Antonio ; Molina Montes, Esther ; Huerta, José María ; Ardanaz, Eva ; Dorronsoro, Miren ; Sjöberg, Klas ; Ohlsson, Bodil ; Khaw, Kay - Tee ; Wareham, Nicholas J. ; Travis, Ruth C. ; Schmidt, Julie A. ; Cross, Amanda ; Gunter, Marc ; Riboli, Elio ; Scalbert, Augustin ; Romieu, Isabelle ; Elena - Herrmann, Benedicte ; Jenab, Mazda

https://doi.org/10.1186/s12916-015-0462-9

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12
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Molecular therapies and precision medicine for hepatocellular carcinoma

Llovet I Bayer, Josep Maria ; Montal, Robert ; Sia, Daniela ; Finn, Richard S.

https://doi.org/10.1038/s41571-018-0073-4

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13
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Translating '–omics' results into precision medicine for hepatocellular carcinoma

Sia, Daniela ; Llovet I Bayer, Josep Maria

https://doi.org/10.1038/nrgastro.2017.103

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14
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Molecular liver cancer prevention in cirrhosis by organ transcriptome analysis and lysophosphatidic acid pathway inhibition

Nakagawa, Shigeki ; Wei, Lan ; Song, Won Min ; Higashi, Takaaki ; Ghoshal, Sarani ; Kim, Rosa S. ; Bian, C. Billie ; Yamada, Suguru ; Sun, Xiaochen ; Venkatesh, Anu ; Goossens, Nicolas ; Bain, Gretchen ; Lauwers, Gregory Y. ; Koh, A. P. ; El - Abtah, Mohamed ; Ahmad, Noor B. ; Hoshida, Hiroki ; Erstad, Derek J. ; Gunasekaran, Ganesh ; Lee, Youngmin ; Yu, Ming - Lung ; Chuang, Wan - Long ; Dai, Chia - Yen ; Kobayashi, Masahiro ; Kumada, Hiromitsu ; Beppu, Toru ; Baba, Hideo ; Mahajan, Milind ; Nair, Venugopalan D. ; Lanuti, Michael ; Villanueva, Augusto ; Sangiovanni, Angelo ; Iavarone, Massimo ; Colombo, Massimo ; Llovet I Bayer, Josep Maria ; Subramanian, Aravind ; Tager, Andrew M. ; Friedman, Scott L. ; Baumert, Thomas F. ; Schwartz, Myron E. ; Chung, Raymond T. ; Tanabe, Kenneth K. ; Zhang, Bin ; Fuchs, Bryan C. ; Hoshida, Yujin ; Precision Liver Cancer Prevention Consortium

https://doi.org/10.1016/j.ccell.2016.11.004 [Peer Reviewed Journal]

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15
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Reply to X. Qi et al ' Brivanib for Hepatocellular Carcinoma Trials: Selection Bias From Barcelona Clinic Liver Cancer Stage?'

Llovet I Bayer, Josep Maria ; Johnson, Philip J.

https://doi.org/10.1200/JCO.2013.54.3033 [Peer Reviewed Journal]

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16
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Objective response by mRECIST as a predictor and potential surrogate end point of overall survival in advanced HCC

Lencioni, Riccardo ; Montal, Robert ; Torre, Ferran ; Park, Joong - Won ; Decaens, Thomas ; Raoul, Jean - Luc ; Kudo, Masatoshi ; Chang, Charissa Y. ; Rios, José ; Boige, Valerie ; Assenat, Eric ; Kang, Yoon - Koo ; Lim, Ho - Yeong ; Walters, Ian ; Llovet I Bayer, Josep Maria

info:eu-repo/grantAgreement/EC/H2020/667273/EU//HEP-CAR [Peer Reviewed Journal]

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17
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BMP9-Induced survival effect in liver tumor cells requires p38MAPK activation

García Álvaro, María ; Addante, Annalisa ; Roncero, Cesáreo ; Fernández, Margarita ; Fabregat Romero, Isabel ; Sánchez, Aránzazu ; Herrera, Blanca

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18
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Trunk mutational events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma

Torrecilla, Sara ; Harrington, Andrew N. ; Sia, Daniela ; Zhang, Zhongyang ; Cabellos, Laia ; Cornella, Helena ; Moeini, Agrin ; Campreciós Figueras, Genís ; Leow, Wei - Quiang ; Fiel, Maria Isabel ; Hao, Ke ; Bassaganyas, Laia ; Mahajan, Milind ; Thung, Swan N. ; Villanueva, Augusto ; Florman, Sander ; Schwartz, Myron ; Llovet I Bayer, Josep Maria

https://doi.org/10.1016/j.jhep.2017.08.013 [Peer Reviewed Journal]

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19
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Strict Selection Alone of Patients Undergoing Liver Transplantation for Hilar Cholangiocarcinoma is Associated with Improved Survival

Mantel, Hendrik T. J. ; Westerkamp, Andrie C. ; Adam, R. (René) ; Bennet, William F. ; Seehofer, Daniel ; Settmacher, Utz ; Sánchez Bueno, Francisco ; Fabregat Prous, Joan ; Boleslawski, Emmanuel ; Friman, Styrbjörn ; Porte, Robert J.

https://doi.org/10.1371/journal.pone.0156127

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20
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Hepatocellular carcinoma

Llovet I Bayer, Josep Maria ; Zucman - Rossi, Jessica ; Pikarsky, Eli ; Sangro, Bruno ; Schwartz, Myron ; Sherman, Morris ; Gores, Gregory

info:eu-repo/grantAgreement/EC/H2020/667273/EU//HEP-CAR [Peer Reviewed Journal]

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